Research library
The research library
Every primary source behind a claim on this site, tier-graded for provenance and tagged for the strength of the evidence it carries.
- Sources indexed
- 221
- Peptides covered
- 44
- Tier 1 share
- 0%
- Matching filter
- 3
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Reset allT2·Peer-secondary literature
Peer-reviewed reviews and cohort/observational work — context, not bedrock.
3 sources
- 2026Meta-analysismoderaten=25,847
Tirzepatide Beyond Diabetes and Obesity: Systematic Review and Meta-Analysis of Multisystem Therapeutic Benefits
Eisa N, Barood O · Endocrine Practice
A 17-RCT, 25,847-patient meta-analysis pooling tirzepatide's multi-organ outcomes: cardiovascular non-inferiority versus dulaglutide (HR 0.92), 38% reduction in HFpEF death-or-HF-event (HR 0.62), MASH resolution in 62% (RR 5.33), 21.9-event/hour drop in apnea-hypopnea index, 5.8 mm Hg SBP reduction, +1.5 mL/min/year eGFR preservation, and 32.9% hsCRP reduction.
- 2022Meta-analysismoderaten=135,874
Treatment with glucagon-like peptide-1 receptor agonists and incidence of dementia: Data from pooled double-blind randomized controlled trials and nationwide disease and prescription registers
Nørgaard CH, Friedrich S, Hansen CT, +9 · Alzheimer's & Dementia Translational Research & Clinical Interventions
Pooled cardiovascular-outcome trials (n=15,820) reported dementia HR 0.47 (95% CI 0.25–0.86) with GLP-1 RA randomization; the parallel Danish nationwide registry of 120,054 patients returned HR 0.89 per year of GLP-1 RA exposure — the load-bearing observational signal that motivated the EVOKE and ELAD interventional programs.
- 2018Meta-analysismoderaten=1,879
Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials
Bornstein NM, Guekht A, Vester J, +7 · Neurological Sciences
Bornstein 2018 is the manufacturer-aligned meta-analysis that pooled nine Cerebrolysin RCTs across 1,879 patients on the primary NIHSS analysis and reported superiority on NIHSS at day 30 — the positive synthesis the Cochrane review reads more skeptically.