Peptide encyclopedia
Every compound indexed here carries mechanism, route of administration, half-life, legal status, and the primary sources backing every claim — graded and dated.
- Compounds
- 75
- Source links
- 249
- Therapeutic classes
- 10
- Matching filter
- 2
F·Filter
Reset allMitochondrial
Mitochondrial-membrane and bioenergetics-axis peptides.
2 compounds
01
Research use only
MOTS-c
Mitochondrial open reading frame of 12S rRNA-c
MOTS-c is the first mitochondrial-encoded peptide to be characterized as a hormone-like signaling molecule — encoded inside the mitochondrial 12S rRNA, secreted into circulation, and reported to regulate insulin sensitivity through AMPK.
Half-life·Brief plasma half-life on subcutaneous administration; in mo…
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02
Prescription only
SS-31
Elamipretide · Bendavia · et al.
SS-31 is the only peptide on this site that targets the inner mitochondrial membrane directly through cardiolipin binding — and the only one whose pivotal Phase III trial in its lead indication missed its primary endpoint.
Half-life·~2.5 to 4 hours plasma half-life on subcutaneous administrat…
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