Peptide encyclopedia
Every compound indexed here carries mechanism, route of administration, half-life, legal status, and the primary sources backing every claim — graded and dated.
- Compounds
- 75
- Source links
- 249
- Therapeutic classes
- 10
- Matching filter
- 3
F·Filter
Reset allSexual function
Melanocortin-receptor activity and sexual-function indications.
3 compounds
01
Prescription only
Oxytocin
OXT · Pitocin · et al.
Pitocin in the obstetric ward is one of the most-used medications on earth. Intranasal oxytocin for social cognition is one of the most-replication-troubled stories in modern neuroscience — and the most-rigorous test of the biohacker-relevant hypothesis, the 290-participant Sikich 2021 NEJM trial in autism, was negative on its primary endpoint.
Half-life·Plasma half-life on the order of 1–6 minutes following intra…
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02
Prescription only
PT-141
Bremelanotide · Vyleesi · et al.
PT-141 is the only peptide on this list approved by the FDA specifically for sexual function — and the only one whose pivotal Phase III evidence (RECONNECT, n=1,267) is in women, while the dominant biohacker conversation is about off-label male use.
Half-life·~2.7 hours plasma half-life on subcutaneous administration; …
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03
Prescription only
hCG (human chorionic gonadotropin)
human chorionic gonadotropin · Pregnyl · et al.
An FDA-approved peptide hormone whose biohacker-popular use case — preserving fertility and testicular function during testosterone replacement — is mechanistically defensible, evidence-anchored at the dose-response level, and entirely off-label.
Half-life·~24 to 36 hours terminal plasma half-life after intramuscula…
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